The successful candidate will conduct a PhD project within aptamer research, more precisely evolution of LNA-containing aptamers. LNA (locked nucleic acid) is a nucleotide analogue which has found widespread use within drug discovery and biotechnology. This PhD project will be an integral part of the activities of the nanomedicine research centre NanoCan. The PhD project will include synthesis of triphosphate derivatives of LNA nucleosides, LNA-containing oligonucleotides, evolution of LNA-containing aptamers, and binding studies against different molecular targets.
The preferred candidate should have a background with documented research experience within nucleic acid chemistry and/or biotechnology and/or molecular biology.The university encourages all persons interested in the position to apply, regardless of their age, gender, religious affiliation or ethnic background.